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Πλοήγηση ανά Θέμα "Models, Animal"

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    • Efficient liver gene transfer with foamy virus vectors 

      Zacharoulis, D.; Rountas, C.; Katsimpoulas, M.; Morianos, J.; Chatziandreou, I.; Vassilopoulos, G. (2013)
      Liver gene transfer offers hope for the correction of genetic and acquired disorders. Efficient gene transfer in large animals can be obtained with hydrodynamic gene transfer (HGT), a method that can achieve sufficient ...

    • An Experimental Model on the Biomechanical Behaviour of the Flexor Tendons in New Zealand Rabbits 

      Skouteris D., Magnissalis E., Papalois A., Varitimidis S., Papagelopoulos P.J., Zoubos A.B. (2017)
      BACKGROUND: In order to introduce new pharmacological agents with the intent to inhibit the adhesion formation, it is important to test such products on laboratory animals under a protocol that can evaluate the quantitative ...

    • LaGomiCs - Lagomorph Genomics Consortium: An International Collaborative Effort for Sequencing the Genomes of an Entire Mammalian Order 

      Fontanesi L., Di Palma F., Flicek P., Smith A.T., Thulin C.-G., Alves P.C., Abrantes J., Andersson L., Angelone C., Boonstra R., Campos R., Carneiro M., Casadio R., Cervantes F.A., Dahal N., Djan M., Esteves P.J., Etherington G., Fan J., Fickel J., Ge D., Husband T., King T., Kovach A.I., Lavazza A., Letty J., Lissovsky A.A., Mage R., Mamuris Z., Martelli P.L., McGreevy T., Jr., Melo-Ferreira J., Muffato M., Ramakrishnan U., Randi E., Reid N., Ribani A., Robinson T.J., Russello M.A., Schiavo G., Schneider-Gricar V., Solari K.A., Streeter I., Tizzani P., Tur A., Utzeri V.J., Velickovic N., Vernesi C., Yang Q., Lagomorph Genomics Consortium (2016)
      The order Lagomorpha comprises about 90 living species, divided in 2 families: the pikas (Family Ochotonidae), and the rabbits, hares, and jackrabbits (Family Leporidae). Lagomorphs are important economically and scientifically ...

    • A low-protein, high-carbohydrate diet increases browning in perirenal adipose tissue but not in inguinal adipose tissue 

      Pereira M.P., Ferreira L.A.A., da Silva F.H.S., Christoffolete M.A., Metsios G.S., Chaves V.E., de França S.A., Damazo A.S., Flouris A.D., Kawashita N.H. (2017)
      Objective The aim of this study was to evaluate the browning and origin of fatty acids (FAs) in the maintenance of triacylglycerol (TG) storage and/or as fuel for thermogenesis in perirenal adipose tissue (periWAT) and ...

    • Minimal invasive technique for gene delivery in porcine liver lobe segment 

      Katsimpoulas, M.; Zacharoulis, D.; Rountas, C.; Dimitriou, C.; Mantziaras, G.; Kostomitsopoulos, N.; Habib, N.; Kostakis, A. (2011)
      Introduction: The feasibility and outcome of large volume injection of gene solution in a segment of a liver lobe, without backflow, were studied in a porcine model, using a custom-designed balloon catheter. Method: Eight ...

    • Pesticides, cognitive functions and dementia: A review 

      Aloizou A.-M., Siokas V., Vogiatzi C., Peristeri E., Docea A.O., Petrakis D., Provatas A., Folia V., Chalkia C., Vinceti M., Wilks M., Izotov B.N., Tsatsakis A., Bogdanos D.P., Dardiotis E. (2020)
      Pesticides are widely-used chemicals commonly applied in agriculture for the protection of crops from pests. Depending on the class of pesticides, the specific substances may have a specific set of adverse effects on humans, ...

    • The role of flavonoids in inhibiting Th17 responses in inflammatory arthritis 

      Kelepouri D., Mavropoulos A., Bogdanos D.P., Sakkas L.I. (2018)
      Flavonoids have been considered powerful anti-inflammatory agents, and their exact immunomodulatory action as therapeutic agents in autoimmune diseases has started to emerge. Their role in the manipulation of immunoregulation ...

    • Transcriptome Analysis Identifies Immune Markers Related to Visceral Leishmaniasis Establishment in the Experimental Model of BALB/c Mice 

      Agallou M., Athanasiou E., Kammona O., Tastsoglou S., Hatzigeorgiou A.G., Kiparissides C., Karagouni E. (2019)
      Visceral leishmaniasis (VL) caused by Leishmania donovani and L. infantum is a potentially fatal disease. To date there are no registered vaccines for disease prevention despite the fact that several vaccines are in ...

    • What is considered cardiotoxicity of anthracyclines in animal studies 

      Georgiadis N., Tsarouhas K., Rezaee R., Nepka H., Kass G.E.N., Dorne J.-L.C.M., Stagkos D., Toutouzas K., Spandidos D.A., Kouretas D., Tsitsimpikou C. (2020)
      Anthracyclines are commonly used anticancer drugs with well.known and extensively studied cardiotoxic effects in humans. In the clinical setting guidelines for assessing cardiotoxicity are well.established with important ...

    • What will the future hold for artificial organs in the service of assisted reproduction: prospects and considerations 

      Simopoulou M., Sfakianoudis K., Tsioulou P., Rapani A., Giannelou P., Kiriakopoulos N., Pantou A., Vlahos N., Anifandis G., Bolaris S., Pantos K., Koutsilieris M. (2019)
      Assisted reproduction provides a wide spectrum of treatments and strategies addressing infertility. However, distinct groups of infertile patients with unexplained infertility, congenital disorders, and other complex cases ...